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An excess variance rule lowered prediction loss for HFO counts in 135 excluded SEEG sleep records from seven patients under record exchangeability

We tested prediction of released HFO overlap counts in 135 five-minute SEEG sleep records from seven patients. Each complete record was excluded before fitting. A fixed rule for excess count variance was compared with a constant Poisson rate rule that included rate estimation uncertainty. The rules used only other records from the same patient. Mean negative log prediction probability fell from 3.027 to 1.851 natural log units per channel per record. Each patient had equal weight. Loss was lower in all seven patients. The mean difference was -1.176. The exploratory 95 percent patient bootstrap interval was -1.999 to -0.512. The exact two-sided sign-flip test gave p = 0.015625 under independent patient effects and null sign symmetry. Count interval coverage rose from 84.41 to 94.47 percent. The alternative intervals contained 97.93 percent model probability, so a calibration gap remained. The result applies to excluded records under exchangeability within this source sample. It does not test later-time prediction, detector accuracy, or surgical outcomes. The package preserves source annotations, versions, hashes, code, every prediction, checks, and reproduction instructions.

high frequency oscillations · stereoelectroencephalography · count prediction · negative binomial model · record exchangeability · epilepsy

Admitted 5 citing publications

References

6
  1. usessci:sha256:73e42f2543dcded2b2577ecbc89c09eac8e76acdb88dd38622ed338522d5588e not known to Sciscape

    We reused its verified source archive for OpenNeuro ds003498 version 1.1.1 and its retrieval script. These files supplied event annotations, headers, channel metadata, source URLs, and hashes for a new test of excluded-record count predictions.

  2. usessci:sha256:74e22fdac1f333c2b0ddb2a290f381a26fb548555b4502c3a28eb34f5d53248c not known to Sciscape

    Its test of count variation inside sleep records helped define the prediction question. We reused source selection evidence and electrode scheme text through the later source archive. The present endpoint is prediction of a complete excluded record, rather than count variance inside a record.

  3. usessci:sha256:a22be20f9664505ea33080cefb407ff7b6665b5b75e6cc0193ba4ef160713581 not known to Sciscape

    Its comparison of HFO channel list agreement inside and between records helped motivate exclusion of complete records. We tested count prediction probabilities in the same public source cohort and did not treat this as an independent cohort replication.

  4. usesdoi:10.18112/openneuro.ds003498.v1.1.1

    The analysis used released HFO annotations and channel metadata from OpenNeuro ds003498 version 1.1.1.

  5. usesdoi:10.6080/K06Q1VD5

    The publication identifies CRCNS ieeg-1 as the original data release underlying the OpenNeuro source.

  6. supportsdoi:10.1038/s41598-017-13064-1

    The source study supports the description of subjects 02 through 09 as patients with temporal lobe epilepsy and depth electrodes only.

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