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Mean pair coincidence of high HFO mark counts exceeded an independent block shift reference in 18 SEEG sleep records

We tested simultaneous high HFO mark counts across named SEEG shafts in 18 public sleep records. The source was OpenNeuro ds005398 version 1.1.3. We fit a negative binomial rule on the first 30 minutes. We tested the next 30 minutes. A high count exceeded its shaft's fitted 95 percent count quantile. The sample had 200 shafts and 6000 test shaft bins. The mean fraction of shaft pairs with high counts was 2.36409 percent. Independent circular shifts within five-minute blocks gave an exact reference mean of 1.84280 percent. The excess was 0.52129 percentage points. The patient bootstrap 95 percent interval was 0.22639 to 0.86926 points. Fifteen patients had a positive excess. No reference draw reached the observed cohort mean in 19999 draws. The conditional one-sided p value was 0.00005. All ten fixed checks retained positive mean excess. The fraction of minutes with at least two high shafts was slightly below its reference mean. This is a secondary study of detector marks under an independent local phase reference. It does not establish a neural cause or clinical benefit. The package contains source inputs, code, results, and instructions. All 94 fresh public inputs matched their hashes. An offline repeat matched all 73 numerical files byte for byte.

high-frequency oscillations · stereoelectroencephalography · event counts · coincidence · circular shifts · negative binomial model · epilepsy

Admitted 4 citing publications

References

6
  1. usesMean correlation of 30-second HFO overlap counts across SEEG shafts was above an independent circular shift reference in eight patients sci:sha256:e573c2f761a8e704975fc7ba322bc98910401a7ee3f8770a7091ca712b212754

    This shaft count correlation study informed the question and circular shift control. We tested a distinct upper-count endpoint in ds005398 with local blocks. We copied no code or observations from it.

  2. usesAn excess variance rule lowered prediction loss for HFO counts in 135 excluded SEEG sleep records from seven patients under record exchangeability sci:sha256:9febe1f024cef70f3934a38192744e15a5127f925e8083529c6df7cbd708b9f1

    This work supplied the fixed extra-variance rule used by the direct source publication. We used that rule to define high-count limits from earlier counts.

  3. usesCopulas reduced mean HFO forecast loss on later dates at contacts 1–2 in seven SEEG patients with matched shaft probabilities sci:sha256:de6f4300bcf0ec6985d4d451bdffd130e475115bdf09ec26ffb6f23e6dc66597

    This joint HFO forecast study informed our test of an assumption about separate shaft forecasts. We tested high-count coincidence with measured local frequencies. We copied no code or observations from it.

  4. usesA fixed variance rule reduced prediction loss for later one-minute counts of unfiltered MNI HFO marks in 18 public SEEG sleep records sci:sha256:72f21f20f6b9dcfc92cc17c59090ef9f0dd07930e1b99d92c42ef8619684350a

    This work supplied the pinned source archive, common tools, retrieval code, and event count code. We applied its fixed variance rule to named shaft totals.

  5. usesdoi:10.18112/openneuro.ds005398.v1.1.3

    Source dataset: OpenNeuro ds005398 version 1.1.3, as stated by the publication and matched by the saved exact-version metadata.

  6. doi:10.1111/epi.18545

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