A five-pulse stability gate selected choices with less observed later score loss in eight SEEG participants at 100 to 500 ms under a half-energy rule
We tested whether a stability gate can identify reliable stimulation-site choices from five calibration pulses. We used public STReEF SEEG data from eight people with focal epilepsy: 31 candidate groups and 258 target tasks. The site rule selects the largest target-to-other-shaft score among candidates with at least half the maximum target energy. The primary window is 100 to 500 ms. The gate accepts a choice only if removing any one calibration pulse leaves the choice unchanged. It accepted 149 targets. On five separate later pulses with reversed recorded contact order, accepted choices had 0.692 percentage points less observed spatial score loss than uniform random target acceptance at the same count. Each group and person has equal weight. The descriptive 95% person bootstrap interval was 0.051 to 1.278 points; the two-sided sign-flip value was 0.09375. This does not establish a reliable population benefit. A secondary later target-energy failure rate was 7.11% for accepted choices and 15.05% for the control. The earlier 20 to 100 ms window did not show the same benefit. The gate rejected 42% of targets. Time and recorded contact order change together, and most candidate test pulses precede completion of group calibration. This is an offline diagnostic association, not a clinical or prospective device test. The package preserves exact pulse products, all choices, figures, source code, data pins, and repeat instructions. Fresh source checks verified all 960 raw ranges. Independent arithmetic, split checks, and a repeated analysis passed.
stereoelectroencephalography · brain-computer interface · single-pulse stimulation · stability gate · site selection · target acceptance · response score · focal epilepsy
References
6- usesTwo versus five calibration pulses changed 54 of 258 SEEG site choices under a half-energy rule in eight people at 100 to 500 ms sci:sha256:370cd22e361cbe077a9f0528875f59ecd777da8d2fea4150778b756a10ebe64b
This study reuses all 19 compact data files, the fixed 96 conditions, common-panel group rules, input utilities, and source recipes. It adds a pulse-omission stability gate and a random target acceptance control. All 1,032 full-five choices matched the input study.
- usesSigned SEEG alignment at 20 to 500 ms exceeded a before-pulse control in eight people after contact order reversal sci:sha256:566477652590c53f83112c199b70fdca7b0e1f47861e04e334107dda534bae03
The reused native pulse products, waveform audit examples, pinned raw ranges, and source reader came from this study through the immediate input publication. The new work freshly checked all 960 source ranges.
- usesA half-energy site rule did not show a clear later target score gain in seven SEEG patients at 100 to 500 ms sci:sha256:ac3c6c7a346cabf2b6b585b10999001bcd22a9558eff31f726620561c2f804a9
The site choice rule uses a relative target-energy floor of one half, then maximizes the target-to-other-shaft score. This method is used through the immediate SEEG input study. No voltage data from this method publication are used.
- usesdoi:10.18112/openneuro.ds005448.v1.0.0
The study analyzes STReEF OpenNeuro ds005448 version 1.0.0, using eight SEEG participants and the archived pulse products and source recipes.
- doi:10.1016/j.ynirp.2025.100274
- doi:10.1007/s12021-022-09567-6
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