Signed SEEG alignment at 20 to 500 ms exceeded a before-pulse control in eight people after contact order reversal
Eight people with focal epilepsy had greater signed SEEG alignment after stimulation than before it after contact order reversal. The study used 960 pulses, 96 conditions, and 6,803 readout-condition rows from STReEF ds005448 version 1.0.0. The mean normalized signed product at 20 to 500 ms was 0.0955. The before-pulse value was -0.0040. The mean difference was 0.0995, with a 95 percent person-resample interval of 0.0571 to 0.1458. All eight differences were positive. The exact two-sided sign permutation p value was 0.0078125. Separate pulse products remove diagonal noise terms from even and odd energy estimates. Unscaled estimates are unbiased only with fixed order means and zero expected noise products between different pulses. The mean normalized even and odd estimates were 0.1103 and 0.0148. A fixed earlier template had less error than its inverse in all eight people. It beat a zero waveform in only one person. Mean normalized errors were 1.1149 for the fixed template and 1.0113 for zero. This supports a sign check, not a useful fixed-amplitude forecast. Contact order and time were linked. The analysis does not establish a neural source or a clinical benefit. The package includes code, figures, products, source hashes, and complete fresh checks of the 960 source ranges.
stereo-EEG · single-pulse stimulation · sign alignment · pulse products · signal processing · focal epilepsy
References
6- usesA scale fit from one pulse lowered mean SEEG forecast error in six of eight sessions after contact order reversal at 20 to 500 ms sci:sha256:18c6ed2417c8fa21e9a22c8580a0e0bf89683a8de79f7dbda88c0cbd316fe6c2
This study reused the fixed metadata sample, pulse product arrays, source headers, and pinned raw range records. A fresh retrieval checked all 960 source ranges. The new analysis used all eligible readouts and did not reuse the response selection gate.
- usesA five-pulse check selected SEEG pairs with 60.8% mean shape agreement after contact order reversal at 20 to 500 ms in eight sessions sci:sha256:35cdaeabceeac5a3be97a54a264240386954c3bac2e4558f03b24d86d28e2bee
This study reused the original metadata selection and pulse extraction code. The package retains that code and its license. An adapted extractor checked native waveform products and the source bytes. The earlier response gate was not used.
- usesdoi:10.18112/openneuro.ds005448.v1.0.0
This versioned STReEF dataset is the recorded source for the analyzed SEEG data.
- doi:10.1101/2023.05.09.23289729
- supportsdoi:10.1016/j.ynirp.2025.100274
The source study describes the 13-person cohort, recording types, clinical stimulation, and acquisition method.
- usesdoi:10.1007/s12021-022-09567-6
The source dataset requests credit for this RESPect data workflow.
Cited by
7 publicationsPublic catalog entries on Sciscape.
- usesMean corrected SEEG change score was greater at 20 to 100 ms than at 100 to 500 ms after contact order reversal in eight people
Reuses the fixed 96-condition sample, source pins, range transport code, metadata, and edge tables. New raw retrieval matches all 960 range hashes and the early and late product arrays exactly. Adds matched before windows and a new corrected early-minus-late change contrast.
- usesSEEG dispersion from five pulses showed no clear mean excess change after contact order reversal at 20 to 500 ms in eight people
We used its fixed 96-condition SEEG sample, exact pulse products, native waveform examples, source records, and source check code. These inputs enabled the new dispersion comparison and forecast error decomposition. This study reuses the cohort.
- usesTwo versus five calibration pulses changed 54 of 258 SEEG site choices under a half-energy rule in eight people at 100 to 500 ms
Exact pulse products, audit waveforms, source metadata, raw range pins, and source code supplied the inputs. We tested a new calibration budget question with the same eight people and pulses.
- usesFive-pulse Hann forecasts at 100–500 ms had 18.7 points more excess skill at 4–30 Hz than at 70–110 Hz in eight SEEG patients
Its signed alignment result in a different SEEG cohort supplies context for the distinction between sign transfer and improvement over zero. The report states that this caution and the squared-error expansion are not new general results. Its numerical input files were not reused.
- usesA five-pulse stability gate selected choices with less observed later score loss in eight SEEG participants at 100 to 500 ms under a half-energy rule
The reused native pulse products, waveform audit examples, pinned raw ranges, and source reader came from this study through the immediate input publication. The new work freshly checked all 960 source ranges.
- usesWith local time centering, equal windows raised mean early SEEG variance ratios from 0.46 to 1.01 in eight STReEF patients
Uses inherited source range transport code and pinned source receipts through the direct parent package. This analysis uses new residual variance products rather than the earlier signed alignment score. Earlier code credit and license records are retained.
- usesA scale from five early pulses reduced full template SEEG error at 20 to 500 ms after contact order reversal in eight people
This study uses the frozen pulse products, selection, source receipts, and source checking code from this report. Its full-template result was known before the local plan and motivated the new early pulse scale.