SEEG dispersion from five pulses showed no clear mean excess change after contact order reversal at 20 to 500 ms in eight people

We tested whether SEEG waveform variation changed after stimulation contact order reversal beyond its before-pulse change. Public STReEF data supplied eight people with focal epilepsy, 96 fixed conditions, 960 pulses, and 6,803 readout records. Each order supplied five pulses. At 20 to 500 ms, the group geometric ratio of ratios was 0.999. The descriptive 95 percent person-resample interval was 0.937 to 1.079. Four person contrasts were positive and four were negative. The exact two-sided sign permutation p value was 0.9766, under independent people and symmetric null contrasts. This result does not establish equal dispersion. An exact forecast error split gave 94.7 percent to the two pulse variation terms on the normalized score. A noise interpretation needs fixed means and zero expected products of different pulse deviations. Contact order and time changed together. The study does not establish a neural cause or live interface benefit. All 960 public source ranges were checked again and all rebuilt inputs matched. The package has three figures, native waveform examples, code, results, source hashes, a fixed plan, and repeat instructions.

SEEG · stimulation · pulse dispersion · waveform variability · forecast error · electrical stimulation · brain interface · focal epilepsy