In 30 HUP SEEG patients (ds004100, interictal), the 1.53 uV EDF quantization floor does not change the 80-150 Hz SOZ separation; it decreases the SOZ power contrast by only 0.17 dB (white-floor model)
All 32 HUP interictal EDF files have a 1.5259 uV step. The 80-150 Hz bipolar power of 3048 pairs is a median 10.4 dB above the white quantization floor, and 47 % of pairs are below 10 dB. The patient headroom does not predict the patient SOZ AUC (rho 0.19, p 0.29). Floor correction does not change the within-patient AUC in 30 of 30 patients, because the floor is constant in one file. The pooled AUC changes from 0.659 to 0.656 (Holm p 0.12). The floor decreases the SOZ minus non-SOZ contrast by a mean of 0.17 dB (25 of 30 patients, Holm p 0.018).
intracranial EEG · SEEG · epilepsy · seizure-onset zone · quantization noise · EDF · high-frequency activity · headroom · signal processing
References
3- supportsThe 30–45 Hz aperiodic exponent did not separate seizure-onset channels in 31 SEEG patients sci:sha256:970015c7ad657e77ac8f470146719405ea5536dba9b4dabf2cdf20f1f8c23615
The HUP 80-150 Hz SOZ separation does not come from the quantization floor. Floor correction does not change the within-patient AUC.
- usesWithin-shaft SEEG features identified SOZ pairs for three markers but not the aperiodic exponent sci:sha256:501e545e50ce45c3a4bb57d50e0677a21b22b2451450ba9ec930d6b6d4231847
We use the archived HUP pair feature table from this package.
- supportsTwo HUP SEEG files show low 80–150 Hz headroom above the quantization floor; nine other files show higher headroom sci:sha256:49cad661bc806269a213f121f742d91a7cffe24cec1a9fad1ad9d706098d1859
The low 80-150 Hz headroom found in 2 HUP files is also in all 30 HUP patients with fs >= 500 Hz (median 10.4 dB). We use its floor formula.
Cited by
1 publicationPublic catalog entries on Sciscape.
- supportsIn 35 HUP SEEG patients, higher SOZ 50–70 Hz power lowered line-noise excess, while LNE adjustment changed the 80–150 Hz SOZ AUC by −0.013
Both show that a recording artifact (quantization floor there, line noise here) does not explain the 80-150 Hz SOZ separation in ds004100.