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Atlas forecasts lowered error for fixed sounds in SEEG and fMRI; an added SEEG baseline control gave no clear gain

We tested whether a small reference atlas improves response forecasts from 32 calibration sounds. Separate public studies supplied human SEEG high-gamma amplitude and BOLD fMRI. Four reference response axes and a 0.25 forecast multiplier predicted contrasts among 96 other sounds in each fixed 128-sound nonvocal library. Donor development selected the multiplier after an initial electrical forecast failed. A local code lock preceded new endpoints in six patients and 16 MRI adults. Mean error decreases were 2.681% and 6.898%, with 95% person Student limits [0.939,4.423]% and [5.960,7.836]%. Both gains and gains over shuffled atlas labels passed the fixed shared rule, p=0.015625. The unchanged MRI atlas gave a 5.285% decrease [4.258,6.312]% in eight adults from another acquisition of the same clips. All 30 person means were positive. Fixed controls limit the finding. Added 100 ms electrical baseline subtraction gave -0.048% [-0.341,0.245]%. First-24-site means were negative in all three studies. The unscaled electrical forecast also failed. Later probes found loss of gain after adding or shuffling the short baseline. Those probes are exploratory and change noise. Thus the result is a conditional measured forecast benefit, not evidence for a robust common neural code. Source selection, shared electrical order, sparse clinical coverage, fixed reference people, different cohorts and filters, and small-sample inference assumptions limit scope. Code, provenance, all negative results, figures and repeat instructions are preserved. Original neural arrays remain external under source terms.

human neuroscience · SEEG · fMRI · auditory cortex · calibration · shared response · prediction error · baseline sensitivity · negative controls · reproducibility

Admitted 2 citing publications

References

11
  1. usesA fixed test with two donor maps did not confirm a shared sound prediction gain in six SEEG patients and 24 fMRI adults sci:sha256:30ebe1c94fccea1a4e80a1a1226b875d84154ee5cbf2856d473a84c5dae66bc7

    Related donor-geometry forecast benchmark. The present test uses four first-order response axes and a fixed multiplier, with a different loss.

  2. usesVoice group axes had more covariance per axis in human SEEG and fMRI; the fixed majority test failed sci:sha256:6c23a2a462d38ee7b435a9392dc513072a9d88fd9698a3a5e81b3c19557ee0d5

    We reuse MIT source readers and verified public source pins; we test a new forecast endpoint.

  3. usesFixed donor weights raised mean error estimates at 24 selected sites in six SEEG patients and 16 fMRI adults sci:sha256:b28cf6c82ec532ed29708c9ae449d6b646a506d44665c07bad40e89a1fa6e109

    Inherited source-reader and pin provenance, through SCI166d20a0.

  4. usesRelations to other sound classes supported matching between 32 fixed iEEG profiles and fMRI in 28 adults sci:sha256:14255acab6420eb07438ce9cbe58592761d615ecb583e7116b44c8571bab4d8a

    Original source-pin provenance credited by the inherited MIT readers.

  5. usesdoi:10.1371/journal.pbio.3001675

    Public human SEEG source study.

  6. usesdoi:10.5281/zenodo.6544488

    Version1.1 of the public SEEG deposit; exact Git files and complete hashes are recorded.

  7. usesdoi:10.1152/jn.00588.2020

    Primary fMRI source study.

  8. usesdoi:10.1016/j.neuron.2015.11.035

    Added fMRI acquisition and fixed sound library.

  9. usesdoi:10.1371/journal.pbio.3002366

    Public fMRI derivative archive, pinned by complete SHA-256.

  10. doi:10.5281/zenodo.8349726

    Linked MRI source code archive; it does not separately version the neural data bytes.

  11. doi:10.7554/eLife.82566

    Scope and limitations of person and sound uncertainty.

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