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Cross-group tests did not establish SEEG response map change across six people

This study tested whether disjoint pulse groups show the same multichannel response change after a stimulation block. It used eight blocks from six people in public SEEG dataset ds006065 v1.0.0. The response window was 50 to 250 ms. The mean signed score outside the fitted pre-block map was 0.058057 in scaled squared voltage units. Its descriptive 95% person bootstrap interval was 0.000251 to 0.127220. The exact two-sided sign-flip value was 0.1875. Estimates depended on pulse grouping and selection. The evidence did not establish response map change or stability across these people. Simulations also showed that a noisy fitted map can leave a residual under pure gain change. The package preserves exact trial inputs, fixed source versions and hashes, source retrieval code, independent checks, and four figures. A clean-copy run reproduced all result tables, 160 map arrays, and all PNG figures.

SEEG · intracranial EEG · stimulation response · cross-validation · response map · measurement noise

Admitted 10 citing publications

References

6
  1. usesWith 10 calibration trials, amplitude updates had lower error than waveform replacement at fixed SEEG pairs in six people sci:sha256:5fbf5699f54eed2770f2feed9404402fd27dc4a13216f041c985185e72ab0782

    This study used the preserved source manifest, pinned S3 object versions and full file hashes, copied BIDS metadata, and unchanged original source-code archive. New full-file retrieval produced multichannel pulse inputs. The earlier fixed-pair forecast errors were not used as new observations. The earlier forecast result motivated this direct response-change test.

  2. usesdoi:10.18112/openneuro.ds006065.v1.0.0

    The analysis uses SEEG pulse-response data and source metadata from this exact OpenNeuro release.

  3. doi:10.1038/s41467-025-59417-7

    Source study associated with the OpenNeuro dataset.

  4. doi:10.5281/zenodo.14735080

    The preserved original MATLAB source archive is used to document extraction rate, epoch boundaries, trial counts, and polarity corrections; it was not executed.

  5. supportsdoi:10.1016/j.neuroimage.2015.12.012

    Cited as a basis for the cross-validated distance method described in the report.

  6. supportsdoi:10.1371/journal.pcbi.1005508

    Cited as a basis for the cross-validated distance method described in the report.

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