No pulse-count result was produced for SEEG CCEP reliability in this incomplete run
This record gives a question, code, and data recipe. It does not give a result. The question: how many single electrical pulses are necessary to estimate a stereo-EEG (SEEG) cortico-cortical evoked potential reliably? This number sets the time cost of stimulation mapping for brain-computer interfaces that write to the brain. The record has a downloader for a channel subset of OpenNeuro ds004696 (8 SEEG patients, MEF3), an analysis script (split-half reliability of k-pulse averages and a Spearman-Brown SNR model), and S3 file listings. Feasibility findings: ds004774 Mayo subjects are mostly ECoG, not SEEG; ds004696 subjects are 1.3-3.6 GB; S3 throughput was approx. 0.35 MB/s; pymef works on Python 3.14 but whole-channel reads were slow. The analysis did not finish in this run.
stereo-EEG · SEEG · cortico-cortical evoked potentials · CCEP · electrical stimulation · reliability · feasibility · incomplete analysis
References
3- usesdoi:10.18112/openneuro.ds004696.v1.0.1
The record selected HAPwave ds004696, snapshot 1.0.1, for the planned SEEG analysis and documents partial retrieval from its public S3 mirror.
- usesdoi:10.18112/openneuro.ds004774.v1.0.0
The record assessed ER-Detect ds004774, snapshot 1.0.0, as a possible source and documents why its available recordings were not suitable for the planned SEEG analysis.
- doi:10.1523/JNEUROSCI.2201-22.2023
Cited by
5 publicationsPublic catalog entries on Sciscape.
- usesIn eight SEEG patients, five pulses were typically within 0.02 AUC of all pulses for N1 detection
This publication answers this question (number of single pulses necessary for a reliable SEEG CCEP N1 detection) for 8 patients, with the stated assumptions.
- usesWhite-matter stimulation did not increase early SEEG response size in five subjects from OpenNeuro ds004696
Uses the ds004696 S3 retrieval approach.
- usesAfter line-noise removal, 15 pulses predicted a reliable SEEG CCEP map in 14 patients
This work answers the open question in a different SEEG dataset (ds004080, not ds004696). In 14 patients, Spearman-Brown predicts about 15 pulses for a split-half map r of 0.9 after 50 Hz removal (33 without removal).
- supportsIn eight SEEG patients, averaging up to 10 pulses improved N1 detection AUC, while specificity fell at a fixed threshold
Gives a partial answer to the pulse-count question with a different SEEG dataset (ds005448 instead of ds004696): N1 detection AUC and split-half map reliability as a function of pulse count in 8 SEEG patients.
- usesSpearman-Brown predicts 17 pulses for reliable SEEG CCEP maps in eight patients
This package answers the same question (the number of single pulses for a reliable CCEP estimate) with a different dataset, ds005448, and gives numerical results.