The estimated mean change in hippocampal theta load slope across delay halves was 0.118 dB per two letters in 12 SEEG patients
We tested whether hippocampal theta load associations change across a verbal memory delay. We used public OpenNeuro ds004752 version 1.0.1. The first two sessions gave 12 epilepsy patients, 44 matched bipolar contact pairs, and 983 retained trials. The primary outcome compared the first and second halves of the three-second delay. We adjusted for trial order and the preceding error. Each patient had equal weight. The estimated mean late-minus-early load slope was 0.118 dB per two letters. The 95 percent t interval was [-0.258, 0.493] dB. The exact two-sided sign-flip p value was 0.497559. The test assumes independent patients and sign symmetry under the null. It did not detect a nonzero mean change. This result does not establish equal load slopes. Load followed an adaptive rule after errors. The estimates are associations. The package preserves code, spectra, trial features, raw examples, fixed source URLs, full source hashes, and independent checks. All 24 source files passed their snapshot hash checks.
hippocampus · theta power · verbal working memory · SEEG · load association · delay timing
References
3- usesLate bipolar hippocampal theta load slopes had a correlation of 0.151 between the first two task sessions in 12 SEEG patients sci:sha256:a924ce7fee66f1151c8a74b7eade8acb9d23fd494af3d197445d7b53543d02dd
We used the matched contact rule, pinned source metadata, complete source hashes, and fixed S3 object versions to extract new early and late delay windows. No parent power features entered the new models.
- usesdoi:10.18112/openneuro.ds004752.v1.0.1
This is the recorded version of OpenNeuro ds004752 analyzed in the publication.
- supportsdoi:10.7554/eLife.78677
The source study documents the task timing and adaptive rule after incorrect responses, which frame the interpretation of the delay-window estimates.
Cited by
4 publicationsPublic catalog entries on Sciscape.
- challengesIn 12 SEEG patients, the estimated mean hippocampal 6–8 Hz / 4–6 Hz power ratio load slope was 0.136 dB per two letters during the last two delay seconds
The parent states that every source trial after an incorrect response has four letters. The pinned event tables show 82 such trials at load 4 and eight exceptions among 90 following trials. Five exceptions pass the current-trial filters. This corrects the event claim, not the parent power estimates.
- usesIn 12 SEEG patients, the estimated mean hippocampal 6–8 Hz / 4–6 Hz power ratio load slope was 0.136 dB per two letters during the last two delay seconds
We used the matched contact rule, metadata, full source hashes, S3 object versions, and extraction code. We retrieved the signals again and calculated new lower and higher theta spectra.
- usesA sign flip test did not detect a hippocampal 8–20/4–8 Hz power ratio change from fixation to late maintenance in 12 SEEG patients
This archive supplied early and late one-second delay spectra, full-delay digital bound flags, raw examples, and full-source verification records. We checked its full manifest and used the late spectra in the new fixation-to-maintenance band ratio contrast. Fresh public late records verified every primary source trial.
- usesA fixed line model gave a mean hippocampal theta contrast slope of -0.032 dB per two letters in two sessions of 12 SEEG patients
We read its early and late theta power results to form the question about late-maintenance spectral shape. Its fitted slopes are not inputs to this analysis.
- usesAn affine fit showed a hippocampal theta excess rise across a three-second delay in 12 SEEG patients
Its delay timing comparison informed the question and the limit from encoding in the first delay second. The current endpoint tests residual theta excess between delay seconds, rather than changes in load slopes.