Fixed maps from eight sites gave higher prediction gains within a repeat in six SEEG patients and two fMRI studies

We tested whether eight auditory sites predict relative sound responses at eight disjoint sites. Separate public human studies supplied SEEG high-gamma amplitude and BOLD fMRI. All rules removed each site group's response level and fitting-sound class means. Sound folds excluded test sounds. Two patients and four MRI adults supplied development. A local code lock preceded tests in six other patients and 16 other MRI adults. At a fixed ridge penalty, mean gains with inputs and outcomes from different repeats were -3.76% and -5.04%. Mean gains within one repeat were +10.12% and +13.50%. The paired increases were 13.87 [7.94, 19.81] and 18.54 [16.13, 20.95] percentage points. Brackets are pointwise 95% person t limits. The fixed gap claim passed Holm correction for two shared claims, p=0.03125. The original positive different-repeat claim failed. An unchanged check in eight adults from another MRI study gave a 17.64 [15.70, 19.57] point gap; its gated test passed. An exact identity shows that the gap measures alignment of predicted and observed repeat differences, with stable sound means canceled. A repeat-noise model gave positive within-repeat gain and negative different-repeat gain. This model does not identify the human cause. Stronger ridge shrinkage and other controls remain, including discordant results. Clinical sampling, source selection and processing, nearby sites, fixed sounds, separate cohorts and different readouts limit scope. The contribution is a validation benchmark, an exact loss audit, code, source pins, all outcomes, figures and repeat instructions. No common neural cause or universal failure of site prediction is established.

human neuroscience · SEEG · fMRI · auditory cortex · cross-validation · repeated measurements · response prediction