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Five test pulses did not establish a 4–30 Hz SEEG covariance change between shafts in eight patients under independent pulses with stable means and second moments

We tested noise covariance between electrode shafts after electrical stimulation in eight patients with epilepsy. We used public SEEG data from OpenNeuro ds004696 version 1.0.1. Five early pulses per site set each readout scale. Five separate later pulses supplied the test. The primary sample had 83 sites and 881 readout-site rows. The test used 4–30 Hz Fourier coordinates from 100 to 500 ms after a pulse. Under independent later pulses with stable means and second moments, disjoint pulse pairs estimate squared covariance change without direct-square bias. Mean corrected Q was 0.519; its descriptive 95 percent patient interval was -0.037 to 1.178. The sign-change reference probability was 0.133. The covariance evidence remains uncertain. The direct squared estimate was 2.177. The separate variance ratio was 1.836, with interval 1.389 to 2.457. This exploratory study extends an existing method to a different cohort and spectral representation. The package includes compact data, proof, figures, source pins, fresh source checks, and replay records. It does not test online control.

SEEG · electrical stimulation · noise covariance · Fourier analysis · pulse response · epilepsy

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References

6
  1. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    This report supplies the original eligibility builder and fixed good pulse selection rules. Its source code is preserved for inspection.

  2. usesA five-pulse test did not establish a cross-shaft noise covariance change after stimulation in eight SEEG patients sci:sha256:ac64ed2ad4f89c67d3e451fc116295b7696f34f36ea9939509de83e2f450d198

    We adapt its disjoint pulse pair estimator and conditional expectation proof to a different public cohort and Fourier band coordinates. We do not claim a new estimator or combine the cohort effects.

  3. uses4–30 Hz SEEG variance remained greater after stimulation outside an early response plane in eight epilepsy patients sci:sha256:4e0a00e389aea5abca17ff3342ffafee0158c25370913bed80856b89e41ce7ae

    This report supplies the fixed readout rows, early and later pulse maps, voltage coefficients, native voltage examples, source hashes, and metadata. We preserve those inputs and test a different-shaft covariance change.

  4. usesPaired after-to-before SEEG variance ratios were 1.51 times as large at 4–30 Hz as at 70–110 Hz in eight epilepsy patients sci:sha256:f8e2e43e31aa8c3dc30e483a7b3326a27352569537f8abef6009a2ecd5c5546a

    The complete source retrieval code, Fourier normalization, and extraction code descend from this report through the direct input. We preserve attribution and adapt the verification option to permit roundoff without replacing inputs.

  5. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    This is the exact OpenNeuro version used for the SEEG recordings and compact numerical inputs; the source record identifies version 1.0.1.

  6. doi:10.1523/JNEUROSCI.2201-22.2023

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