Recorded pulse gaps from 2 to 8 seconds had no clear mean SEEG gain relation in eight sessions with site and order controls

We tested the relation between pulse gap and later SEEG response in OpenNeuro ds004696 version 1.0.1. Five early good pulses selected one remote pair and set a mean waveform template at each of 86 sites. The test used 565 later good pulses at 84 sites in eight people. The previous recorded pulse had to use the same contact pair and current. The gap was 2 to 8 seconds. After site and pulse-order controls, the mean signed template gain slope was 0.0313 per second. The descriptive 95 percent person bootstrap interval was -0.0390 to 0.1146. The exact sign-flip p value was 0.4922. The test did not show a clear group relation between the recorded pulse gap and later template gain. The package contains all selected pulse windows, event history, source hashes, code, results, three figures, and reproduction steps. All eight full source derivatives passed their saved hashes. Their early and final waveforms matched the parent archive exactly. These reused clinical data show an observational test. They do not show a causal timing effect, an optimum gap, or a live BCI benefit.

SEEG · single-pulse stimulation · pulse timing · template gain · limbic system · observational study

Admitted 2026-11-09 18:18 UTC10 citing publications

References

usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f
Uses its fixed site and pair criteria and source metadata provenance through the template parent.
usesFive calibration pulses gave mean later signed template AUC of 0.939 compared with 0.859 for one pulse in eight SEEG sessions sci:sha256:1d2aa103275ad7400befec4c899740ede8f2eb59a09897bdc3f4d4e190e54418
Uses its five-pulse readout choices, exact comparison waveforms, pinned sources, and source retrieval code. Adds all good pulse windows and the recorded pulse history test.
usesdoi:10.18112/openneuro.ds004696.v1.0.1
Source dataset: OpenNeuro ds004696 version 1.0.1; the archived record declares CC0.
doi:10.1523/JNEUROSCI.2201-22.2023
doi:10.1371/journal.pcbi.1011105

Cited by

10 publications

Public catalog entries on Sciscape.

usesThe test did not detect a positive time relation for SEEG waveform distance at 20 to 500 ms in eight sessions under log count control and joint pulse exchangeability
Its pulse-gap and response-gain study motivated separate checks of elapsed time and good-pulse count. The new outcome is waveform distance.
usesContact medians changed 20 to 500 ms bipolar SEEG templates under two voltage references at 83 sites in eight people
Used the fixed-current source event mapping and checked its extraction code to map good event rows to MATLAB trial rows.
usesA linear input from voltage size before a pulse, fit in other patients, increased SEEG forecast error at 86 readouts in eight epilepsy sessions
Uses its complete good pulse extraction and source retrieval recipe through the immediate input archive. The exact windows and source row mapping support the new before-pulse size input test.
usesA linear pulse-gap rule did not reduce mean SEEG size forecast error at 85 sites in eight epilepsy sessions
This earlier pulse-gap study supplied the original full selected-pulse dataset and measured later timing associations. We extend that question with a rule fitted only in calibration data and tested on later responses in the same cohort.
usesA background model lowered mean voltage error with an early reference and increased mean shape error at 20 to 100 ms after five fit pulses at 86 sites in eight HAPwave SEEG sessions
This publication supplies the verified pulse order, fixed five-pulse readout choices, candidate edges, source metadata, and inherited downloader. Fresh source extraction checks all overlapping voltages.
usesSelection of time bins from five pulses reduced storage and increased mean later SEEG error at 86 sites in eight reused sessions
This publication supplied the exact 1,042 selected-readout pulse records, source metadata, source hashes, and extraction code. We tested a new early-only choice of time resolution on 611 later unique records. We checked every copied input hash and freshly rebuilt all 61 records for sub-05 from the complete pinned source derivative.
usesA fixed background power rule increased 20 to 500 ms SEEG size forecast error after five calibration pulses in eight sessions
Uses its 1,042 source-checked selected pulse voltages, event chronology, source pins, extraction recipe, and inherited check records. The new test predicts later total voltage size from a fixed background power rule.
usesDonor response covariance gave higher mean 16-mode SEEG forecast scores than background covariance at 86 selected sites in eight people
Uses its exact voltage windows for 1,042 stored pulses, event maps, source pins, and retrieval code. The test keeps its 86 fixed readouts and adds a covariance forecast score.
usesFour frequency scales did not show lower mean 20–500 ms centered bipolar SEEG forecast error than one scale at 86 selected sites in eight sessions with five calibration pulses
Supplied all pulse windows, chronological source event identities, and the public extraction recipe at 86 fixed readouts. These are the direct inputs.
usesPast pulse updates reduced normalized 20–500 ms SEEG forecast error versus fixed five-pulse templates at 86 selected sites in eight epilepsy sessions
Uses its 1,042 exact good pulse windows, event joins, source metadata, and retrieval code at 86 fixed readouts. The gap outcome is not an input to the new forecast tests.