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A fixed background power rule increased 20 to 500 ms SEEG size forecast error after five calibration pulses in eight sessions

We tested whether background power before a pulse improves a fixed forecast of SEEG size after stimulation. We used eight public sessions in OpenNeuro ds004696 version 1.0.1. Five early pulses at each of 86 sites set both forecasts. There were 612 later test pulses. The rule added current background power to a fitted response power term. The reference forecast stayed constant at each site. Mean squared log-size error was higher for the rule in all eight people. The equal-person mean relative increase was 75.4 percent, with a descriptive 95 percent person bootstrap interval of 12.7 to 181.4 percent. The absolute mean increase was 0.0211 square log units. The exact sign-flip p value was 0.00781. Four fixed checks had the same direction in all eight people. One person had a large relative increase. This is an exploratory test on a reused cohort. It concerns total recorded voltage size, not a causal change in neural response or live BCI control. The package contains exact selected voltages, forecasts, models, results, three figures, a proof, source pins, and repeat instructions. New source checks matched 211 pulses and 20 early pair choices in 3 people. Numerical repeat and independent checks passed.

SEEG · electrical stimulation · forecasting · background power · signal processing · brain-computer interface · prediction error

Admitted 18 citing publications

References

5
  1. usesA five-pulse test did not establish lower SEEG size prediction error from pre-pulse RMS in eight patient sessions sci:sha256:947fe7aa6e242e0f9e723e54cb14b472f7f801ecbaac8501e809356a1e6953c5

    Uses its prior result as context for an exploratory question on the reused cohort. The present rule has no fitted state slope and tests all later pulses. It does not repeat that fitted-slope test.

  2. usesFive calibration pulses gave mean later signed template AUC of 0.939 compared with 0.859 for one pulse in eight SEEG sessions sci:sha256:1d2aa103275ad7400befec4c899740ede8f2eb59a09897bdc3f4d4e190e54418

    Uses its first-five-pulse choices of one remote bipolar readout at each of 86 sites. The choices stay fixed for the new forecasts and are rebuilt in new source audits.

  3. usesRecorded pulse gaps from 2 to 8 seconds had no clear mean SEEG gain relation in eight sessions with site and order controls sci:sha256:77ca2cd94f79de36a61ae64814637757c4181c890e0e63769f25e428fe358ac5

    Uses its 1,042 source-checked selected pulse voltages, event chronology, source pins, extraction recipe, and inherited check records. The new test predicts later total voltage size from a fixed background power rule.

  4. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis used the public SEEG sessions from OpenNeuro ds004696 version 1.0.1.

  5. doi:10.1523/JNEUROSCI.2201-22.2023

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