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With fixed readers, mean heat contrast kept more than half its early size in 115 EEG and 19 fMRI adults; the joint drift test failed

A falling neural heat score need not lose its heat contrast. We tested one fixed joint rule in separate public human EEG and fMRI studies. It required a falling mean score and late heat contrast above half the early contrast in both modalities. A public SCI protocol preceded reserved endpoint scores. The joint rule failed, p=0.06811, because the MRI mean-shift interval included zero. The planned retention components were positive in 115 EEG and 19 MRI adults. Mean late-minus-half-early contrasts were 0.259 and 0.455 person score SD. After the joint failure, simultaneous 95% intervals over all six primary components were [0.128,0.391] and [0.135,0.774]. This is a corrected exploratory retention statement, not a replacement primary. Training-and-target person bootstraps kept both retention signs. A later fixed exploratory test in 63 adults from another MRI study also met the bound, p=0.000919. Its mean score rose. All negative people and discordant shifts remain. The result concerns mean standardized contrasts in fixed readouts and source record halves. It does not establish equal early and late responses, a common neural cause, pain specificity or clinical validity. Selected EEG rows, missing exact EEG timing, inherited MRI fits, context assumptions, small MRI training size and different tasks limit scope. The package has licensed compact inputs, source versions and terms, code, all results, source and arithmetic audits, figures and repeat steps. A clean offline repeat matched eight CSV files and six result JSON objects.

EEG · fMRI · heat · pain · habituation · response contrast · measurement · reproducibility

Admitted 3 citing publications

References

13
  1. usesA fixed protocol tests half retention of heat contrast during score drift in human EEG and fMRI sci:sha256:2576b0f0164a3ef615bcc172e74090ca1d3fea0202e53ea828926d24bb5c4112

    Publicly fixes the primary endpoint, split and failure rule before reserved scores.

  2. usesFixed heat scores decreased with retained order in 115 EEG and 20 fMRI adults; resampling training subjects left the fMRI slope uncertain sci:sha256:69f45454a1d67b830b3f8a8169a8701fbb278edf03e3a37e29562cb38976792c

    Supplies permitted main data, readers, splits and input/reader code; its prior order result is known.

  3. usesExploratory record checks in 114 EEG and 87 fMRI adults gave positive heat rank covariance; three primary shared tests failed sci:sha256:06bd2f1b523bdd21df2962abacc6c3fe4ffc905f1461ccd82080508b56a69848

    Supplies the sparse BMRK5 extract, its earlier fixed reader, source map and optional extraction code.

  4. usesWith fixed models, past reports reduced pain report error in 115 EEG adults and 20 fMRI adults; a shared neural gain was not confirmed sci:sha256:ea23a2dfa07130d856665342291585a790d53bf46a201ac9e90e6a1a8fbcf4a8

    Supplies original BMRK4 grid extraction, geometry and source structure checks.

  5. usesNeural scores trained on heat level tracked adjusted pain reports in 115 EEG adults and 20 fMRI adults sci:sha256:23f65a3fa079f4037761d6eb145841339f455f2c424de8f10fe006c3c9f00216

    Intermediate data/reader work in the reused source chain.

  6. doi:10.17605/OSF.IO/BS3YJ
  7. doi:10.1371/journal.pbio.3003948
  8. doi:10.6084/m9.figshare.12795116.v1
  9. doi:10.7554/eLife.15166
  10. doi:10.1097/j.pain.0000000000003052
  11. doi:10.6084/m9.figshare.19491326.v1
  12. doi:10.1038/s41562-020-0819-8
  13. doi:10.1371/journal.pbio.3001620

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