Sound response areas were positive after class mean removal in selected data from six SEEG patients and two fMRI cohorts

We tested whether stable sound differences after broad-class centering can exceed one fixed linear response dimension. Separate public studies supplied three-repeat SEEG high-gamma and BOLD fMRI responses. One repeat fitted two directions. The two other repeats tested a mixed area. A fixed linear rank-one signal has expected area zero under independent zero-mean repeat errors. Development used two patients and four adults. Fixed tests used six other patients and sixteen other adults. Mean areas were 0.022164 and 0.022862, with 95% person intervals [0.012028,0.032300] and [0.015008,0.030715]. All people were positive. Eight adults from a second fMRI study gave mean 0.014611 [0.009636,0.019586]. The shared mean p was 0.00123370; a conservative two-claim Holm value was 0.00246740. Common sound-and-person resampling kept positive ranges. The speech-and-song-only SEEG interval included zero. The before-onset electrical mean was near zero. Independent solvers agreed within 4.45e-16. In a rank-one simulation, selecting sites by repeat reliability gave positive area. The six-record gate rate was 29.43%, versus 2.03% without selection. The fMRI sources had prior reliability selection, so the human result does not establish neural rank above one. These are fixed-panel tests in reused, selected cohorts. Cohort differences, unequal sampling, shared processing and measurement filters limit transfer. We supply code, source versions and terms, all scores, uncertainty, simulations, figures and repeat instructions. Original source arrays remain external.

human neuroscience · SEEG · fMRI · auditory responses · dimensionality · repeat reliability · selection bias · mixed determinant