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Combined sound features gave positive mean gains over both single sets in 11 iEEG patients and eight fMRI adults

We tested whether combined acoustic features and sound category labels give higher prediction scores than either set alone at the same measured auditory site. Public inputs came from separate human intracranial EEG (iEEG) and fMRI studies. We defined J as the combined model signed squared test correlation minus the better single model score at each site. We averaged sites within each person. Exploration of 104 source electrodes in 11 patients gave mean J 0.007454, with a 95 percent person interval of 0.004286 to 0.010379. We fixed a new fMRI fitting and test plan before fMRI response analysis. Nested ridge fits predicted held-out sound identities. Eight adults with three complete scans supplied 9,340 source-selected voxels; two other source adults lacked scan 3 and failed the fixed rule. Mean fMRI J was 0.023122, with interval 0.019087 to 0.026953 and exact one-sided person sign-flip p 0.003906. Nine of 11 patients and all eight fMRI adults had positive means. A separate-scan fMRI check gave a smaller positive mean of 0.010823. Two negative patient means, all site losses, and an uncertain short-integration group result are retained. The shared result concerns fitted prediction at measured sites. It does not show joint coding in single neurons or a common neural cause. Models, sound sets, cohorts, source selection, and spatial scales differ. Person uncertainty conditions on the supplied sounds. Incomplete acoustic features and ridge shrinkage limit interpretation. The package preserves original code, source versions and hashes, the local plan, all derived results, figures, numerical checks, and repeat instructions. Source input files remain external.

auditory cortex · human iEEG · fMRI · natural sounds · model comparison · category labels · cross-modal generalization · ridge regression · held-out prediction

Admitted 15 citing publications

References

4
  1. usesdoi:10.1038/s41562-021-01261-y

    We analyse the public per-electrode held-out prediction table from this study.

  2. usesdoi:10.1016/j.neuron.2015.11.035

    We fit new models to its public sound by voxel by scan response matrix.

  3. usesdoi:10.1016/j.cub.2022.01.069

    We use public acoustic features and sound identities from its source repository.

  4. Full sound filters did not confirm a gain over rank one in six iEEG patients and 25 fMRI listeners sci:sha256:5d8e1588cef40938c49cc8f56af0afd1a96e9f2eca79d1555dffc517f4f83ecc

    We build on its use of fixed cross-modal prediction tests and its separation of fitted model structure from test gains. We reuse no data or code.

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