Bipolar reference changed linear ECG prediction skill in both directions compared with common average reference in nine adult rest SEEG records
We tested whether adjacent bipolar reference reduces linear ECG prediction skill compared with common average reference. We used the first 124 seconds of rest in nine adults with epilepsy from OpenNeuro ds003688, version 1.0.7. The fixed 1–40 Hz model trained on an early block and scored a later block. It used 578 good SEEG contacts and 518 consecutive pairs. Bipolar skill decreased in five adults and increased in four. The equal-adult mean difference was +0.042 percentage points. The 95% participant bootstrap interval was -0.283 to +0.363 points. The exact two-sided sign-flip test gave p = 0.8125. It assumes independent adults and symmetric difference errors. Mean skill was negative under each reference. The supplied reference mean still exceeded all 99 group timing controls. This diagnostic does not identify a cardiac or neural source. The evidence does not show a general decrease in this score with bipolar reference or equivalence of references. The package states the pair rule for 27 pairs with no group label. It preserves code, inputs, provenance, controls, results, and instructions. A second analysis gave identical numeric tables and model arrays. A fresh source check passed for one adult.
stereo-electroencephalography · SEEG · electrocardiogram · ECG · bipolar reference · common average reference · ridge regression · prediction skill · cardiac artifact · OpenNeuro
References
4- usesdoi:10.18112/openneuro.ds003688.v1.0.7
The analysis uses the first 124 seconds of rest SEEG and ECG from this exact OpenNeuro release.
- supportsdoi:10.1038/s41597-022-01173-0
Describes the OpenNeuro clinical intracranial recordings, physiological channels, and rest records used as source data.
- doi:10.1016/j.neuroimage.2018.08.020
- doi:10.1093/cvr%2Fcvaf099
Cited by
14 publicationsPublic catalog entries on Sciscape.
- usesReference changes gave larger average SEEG autocorrelation half-width differences than rest block changes in nine selected adults at 0.5 to 40 Hz
We used its exact nine reduced SEEG input arrays, fixed contact pairs, source metadata, selection audit, source provenance, and retrieval code. These inputs enabled a new comparison of reference and rest block differences in autocorrelation half-width. We did not use its ECG prediction results.
- usesTen seconds of correlation calibration reduced mean Gaussian loss for transferred rest and film SEEG models in nine adults at 64 Hz
This publication supplied the original adult and SEEG selection audit. That inherited selection defines the sample used here.
- usesFixed linear models gave lower mean normalized 500 ms SEEG prediction error within records than between paired rest and film records in nine adults
We used the original adult selection audit to state the screened sample and its limits. The paired source study retained the same nine adults. This cohort reuse does not provide an independent replication.
- usesA circular shift test did not detect late ECG peak template repeatability in nine adult rest SEEG records with bipolar reference
This study uses the exact 128 Hz input arrays, selected channels and pairs, source metadata, provenance, and retrieval code. It tests late event template agreement in the same cohort.
- usesBipolar SEEG waveform projection at ECG candidate times exceeded median timing controls in seven of nine selected adult rest records
This study uses the selected 128 Hz voltage arrays, contact pairs, source metadata, provenance, and retrieval code. It tests a separate waveform score.
- usesFixed ECG models had negative mean test skill in nine adults' rest and film SEEG at 1 to 20 Hz
This publication supplied the fixed nine adult sample, 128 Hz rest signal arrays, source metadata, and selection and retrieval code. We added matched film records and tested ECG model transfer between records.
- usesDelayed ECG event bins reduced mean test skill after fixed linear ECG prediction in nine adult SEEG rest records
Used its nine selected SEEG and ECG arrays, metadata, source provenance, retrieval code, and original base scores. The new study tests delayed event bins added to a fixed linear ECG voltage model. It uses the same adults.
- usesTen seconds of correlation calibration reduced mean Gaussian loss for transferred rest and film SEEG models in nine adults at 64 Hz
This publication supplied the original adult and SEEG selection audit. That inherited selection defines the sample used here.
- usesA fixed ECG correction increased 1–40 Hz SEEG time asymmetry in six of nine adult rest records at a 31.25 ms rank lag
This study reused all nine short SEEG and ECG input archives, metadata selection, source provenance, retrieval code, and fixed model settings. It tested a new ordinal time asymmetry endpoint in the same records. It is not a new cohort replication.
- usesA fixed heartbeat phase model had negative mean beta power skill after linear ECG subtraction in nine adult SEEG rest records
Used its verified reduced SEEG and ECG inputs for nine adult rest records. Used its metadata selection, retrieval code, source identities, and reference pair rule. Tested a new beta power target with a fixed heartbeat phase model. This is the same patient sample as the source voltage study.
- usesFour added cardiac phase harmonics reduced mean SEEG test skill for a fixed ECG model in nine adult rest records
We reused nine fixed 124-second inputs, selection files, source metadata, immutable range identities, and baseline contact scores. These files enabled the phase comparison. All 578 base scores matched the prior scores within numerical tolerance.
- usesAn ECG model trained on early rest replaced a mean 4.14 percent of the top 10 percent of 1 to 40 Hz SEEG links in nine adults at the recorded reference
This secondary analysis uses the nine-patient selection, reduced SEEG and ECG arrays, source metadata, and input check code. It tests a new correlation link outcome in the same patients.
- usesSubtracting fitted ECG covariance gave more error than unchanged covariance in nine early-to-late 1–40 Hz rest SEEG tests
This study supplied the nine-adult selection rules, contact pairs, and fixed ECG ridge model. We kept the cohort and model to test a new covariance endpoint.
- usesA rank-one ECG model gave mixed later prediction gains in nine adult 1–40 Hz rest SEEG records after early penalty selection
This publication supplies the original metadata selection and fixed-penalty ECG prediction context. The present study tests whether a rank constraint improves later prediction when each model selects its penalty from early data.