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Five-pulse signed templates did not show a clear AUC gain over energy on energy-selected pairs in eight epilepsy SEEG sessions

We used public OpenNeuro ds004696 version 1.0.1. The study had eight epilepsy patient sessions, 86 stimulation sites, and 886 eligible bipolar pairs. At each site, five early pulses selected one pair by energy. The same pulses defined a mean after-pulse template. We tested five later after and before windows with both scores on that pair. The window was 20–500 ms after stimulation. Equal patient mean AUC was 0.939 for signed projection and 0.931 for energy. The mean difference was +0.86 percentage points. The exact patient sign-flip test gave p = 0.4531. The exact test does not establish a difference at the 0.05 level. The descriptive 95% patient bootstrap interval was -0.90 to +2.90 percentage points. For 100–500 ms windows, the signed projection difference was +0.55 percentage points. The package preserves exact joint waveform products, selected source waveforms, scores, figures, source hashes, and an offline scoring tool. This reused clinical cohort has no sham input, neural ground truth, or new-session test. The result does not validate a live BCI control rule.

stereoelectroencephalography · electrical stimulation · response monitoring · signed projection · template matching · area under the curve · brain-computer interface · epilepsy

Admitted 7 citing publications

References

4
  1. usesEarly power selection gave 0.931 mean AUC between later after-pulse and before-pulse SEEG windows in eight epilepsy patient sessions sci:sha256:b0d1b4a077fff84e56c767399fe1c933ce7ad2f5c319fa66176fa90683c52a20

    This publication supplied candidate tables, exact within-window products, source hashes, metadata, and retrieval code. They fixed the eligible cohort and readouts selected by early energy. New source retrieval added after-to-before products for the template scores.

  2. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analyzed processed trial voltages came from OpenNeuro ds004696 version 1.0.1.

  3. doi:10.1523/JNEUROSCI.2201-22.2023
  4. doi:10.1371/journal.pcbi.1011105

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