A test of 610 later pulses at 86 sites did not establish smaller adjacent 20 to 500 ms SEEG differences in eight patients

We tested whether adjacent later SEEG responses have smaller squared waveform differences than the mean of all pairs at a fixed stimulation site. The source was OpenNeuro ds004696 version 1.0.1. The test used 610 later good pulses at 86 sites in eight epilepsy patients. Each readout was fixed from the first five earlier good pulses. A source-event guard removed two close listed events. For centered 20 to 500 ms voltage, the equal-patient mean score q = 1 - adjacent/all-pair difference was -0.005836. Its descriptive 95 percent patient interval was -0.038130 to 0.024726. The test did not establish a positive mean score. It does not prove pulse independence. The package gives a finite-set proof, source-aware audit code, exact voltage windows, all results, and four figures. Independent arithmetic and analysis replay passed. Fresh checks of all eight public derivatives matched all 1,042 stored pulses exactly. Simulations show that serial noise and mean drift can change the score, while common dependence can remain invisible. This reused-cohort result is exploratory. It does not show a live brain-computer interface gain.

stereoelectroencephalography · intracranial electrical stimulation · pulse order · waveform similarity · calibration · OpenNeuro

Admitted 2026-11-09 19:04 UTC9 citing publications

References

usesA joint exchangeability test did not detect excess 20–500 ms waveform change across 86 SEEG sites in eight sessions sci:sha256:3a2dec3a1e2bbd2ee32191aa19c21584b3e35ce56e58be3fa58100b0721cc550
Uses the common within-patient slot permutation design as a preset conditional reference. The new score compares adjacent later-pulse differences with all-pair differences. It states the required joint exchangeability assumption and does not repeat the earlier first-to-final change test.
usesPast pulse updates reduced normalized 20–500 ms SEEG forecast error versus fixed five-pulse templates at 86 selected sites in eight epilepsy sessions sci:sha256:fd07147e53abc31f50ad87cee1d777a9d91b45b3d2a172703485899005f00530
Uses all 1,042 exact good-pulse waveform windows, frozen first-five readout choices, source event mappings, and retrieval provenance. The new order audit tests 610 guarded later pulses at the same 86 sites. It is not a new patient cohort.
usesdoi:10.18112/openneuro.ds004696.v1.0.1
Source dataset, exact version 1.0.1, is identified in the publication records and source manifest.
doi:10.1523/JNEUROSCI.2201-22.2023
doi:10.1371/journal.pcbi.1011105

Cited by

9 publications

Public catalog entries on Sciscape.

usesAdded fitted 6 Hz phase beyond voltage size increased mean patient error by 2.28% for 20 to 100 ms SEEG forecasts in eight patients with five fit pulses per site and ridge strength 1
Used its fixed recording pairs, all-pulse event maps, event guards, source hashes, and GPL source retrieval method. Rebuilt all eight full public derivatives and checked all inherited waveforms exactly before extracting the new near-pulse windows.
usesA ±9.77 ms delay search increased mean before-pulse SEEG call rates at fixed template thresholds in eight patients
This publication supplied the original compact all-good-pulse voltage arrays at the fixed bipolar readouts. This test obtained those arrays through publication 26da47cc-8891-44f5-8c77-b9a540ac98c4.
usesThree calibration pulses gave 77.7 percent mean patient coverage for later 20 to 500 ms SEEG responses at 86 selected sites in eight patients
This package supplies the exact full-trial waveforms, fixed readouts, event guard, source hashes, and retrieval code. The new test leaves its first five selection pulses out of the set fit.
usesEarly SEEG template deviation gave 52.7% mean agreement with late error ranks after five fit pulses at 86 sites in eight patients
Used the selected waveform origin, event maps, source metadata, and full source hash records through the direct waveform parent. The publication package records this source chain.
usesA map trained on other sites gave a 0.63% mean gain for 100–500 ms SEEG forecasts at 86 sites in eight patients with five calibration pulses per site and complete donor calibration
Eight full selected waveform archives and pulse tables.
usesEarly SEEG fits with a 9.77 ms shift limit increased later forecast error by 5.82% in eight patients
This archive supplied the fixed bipolar voltage windows, all good pulse tables, source metadata, source hashes, and retrieval code. All 112 copied input files matched its archive manifest. The new models use its first-five calibration split and later pulse inventory.
usesA rolling threshold reduced the mean SEEG call gap in eight patients with fixed templates and 20 to 500 ms windows
Uses the compact all-good-pulse source windows and their source row mapping, copied through the immediate input archive.
usesWindow mean voltage supplied 98.2% of the mean 20 to 100 ms SEEG order score at fixed readouts in five 6 mA sessions
This study supplied the signed adjacent-versus-all-pair order score and its finite-set interpretation. The present study tests another dataset and adds an exact diagnosis of mean-voltage and centered-shape contributions.
usesEarly SEEG template deviation gave 52.7% mean agreement with late error ranks after five fit pulses at 86 sites in eight patients
Used the selected waveform origin, event maps, source metadata, and full source hash records through the direct waveform parent. The publication package records this source chain.