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Up to four class examples reduced mean response pattern error after two amplitude controls in 20 iEEG patients and 16 fMRI adults

We tested whether a few sounds correct response patterns beyond two specified amplitude directions. Separate public studies supplied human iEEG local field potential means and BOLD fMRI estimates. Four patients and four adults supplied development. A local code lock preceded tests in 20 other patients and 16 other adults. Fitting sounds set site scales, an acoustic model and two directions: uniform site activity and the mean fitting response. Correction used 0.25 times the mean error from up to four class examples. Test sounds were excluded from fitting and support. Mean projected error gains were 4.675 [2.501, 6.848] and 8.210 [7.705, 8.714] points of mean-prediction error. Brackets give 95% person Student limits. Positive counts were 16/20 and 16/16. The fixed shared gain test passed, Holm p=0.011818. The mean comparison with acoustically matched other-class examples failed, Holm p=0.082104. One positive electrical extreme made that mean uncertain. One-example electrical gain was also uncertain. Eight adults from another MRI acquisition gave gain 8.248 [7.448, 9.049]; possible person overlap was not resolved. An exact acoustic-interaction model gave a positive projected gain without a semantic variable. Thus the result supports this measured correction procedure, not semantic coding or a common neural cause. Different cohorts, sound sets, source screens, sparse electrical coverage, reference and vascular filters limit scope. Code, allowed inputs, compact statistics, all negative results, source pins, figures and repeat instructions are supplied.

human neuroscience · intracranial EEG · fMRI · auditory cortex · sound classes · response patterns · residual correction · subject inference · public data

Admitted 6 citing publications

References

15
  1. usesA correction from up to four sound class examples lowered mean model error in 20 iEEG patients and 16 fMRI adults sci:sha256:b8582d8a1129c3fb7d8b16f1b24caaa8fdd525603206abb9a5b5390126c09ebe

    We reuse its fixed acoustic model, folds, matched support selection, alpha, licensed electrical inputs and MIT code. We test a new training-only spatial projection endpoint.

  2. Residual sound maps agreed between a fixed iEEG panel and 20 fMRI adults under a rotation reference sci:sha256:c833e2811606e931c209b9a349ce18fad053c6a5d3d1e78c89d2e3e2cb2a83e9

    Its residual geometry result informed the question. Our patient-labelled data and held-out prediction endpoint differ.

  3. usesUp to eight class examples lowered mean acoustic prediction error at fixed panel sizes in human iEEG and fMRI sci:sha256:893206318a69c0c2ee48c620d9c251b75b82c4fd886d1c167ba280a16c3e83c2

    Licensed electrical derivative and source preparation in the input donor chain.

  4. usesSound labels lowered test error for averaged responses in 20 iEEG patients and 16 fMRI adults; separate BOLD fits gave no clear gain sci:sha256:495812fc27afe8b3e0fe67db013b2f4b72cecb708745c383879ab0479511bcad

    Upstream loader and native MRI preparation; a source-model selection caution.

  5. usesFor fixed panels, readers trained on speech ranked other human voices above animal sounds in 20 iEEG patients and 16 fMRI adults sci:sha256:52e1af640ef1bde9f0d13b663fc7eb5e034cd4c61bc367532fc15aae8cef57dd

    Original licensed electrical derivative in the verified SCI input chain.

  6. usesdoi:10.1016/j.cub.2026.07.063

    Human electrical source study.

  7. usesdoi:10.5281/zenodo.20599001

    Version 1.1 of the public Hect data release. Small files and selected neural windows are audited against this source.

  8. usesdoi:10.1152/jn.00588.2020

    B2021 human MRI acquisition study.

  9. usesdoi:10.1016/j.neuron.2015.11.035

    NH2015 human MRI acquisition study.

  10. usesdoi:10.1371/journal.pbio.3002366

    Public author neural archive with both MRI studies. Exact tar bytes are pinned by SHA-256.

  11. doi:10.5281/zenodo.8349727

    Versioned companion code release. This DOI is not claimed to archive the neural data tar.

  12. usesdoi:10.1016/j.cub.2022.01.069

    Pinned acoustic features and 12-class reference labels for MRI.

  13. doi:10.1371/journal.pcbi.1005508

    Established framework for neural response patterns and measurement dependence.

  14. doi:10.1371/journal.pbio.3001675

    Patient-labelled natural-sound data inspected for clip-translation feasibility; no neural endpoints from that source were analyzed.

  15. doi:10.5281/zenodo.6544488

    Version 1.1 inspected for label availability only. Its neural arrays do not enter the final test.

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