Site block pooling increased three-pulse SEEG coverage and mean bound score at 20–500 ms in eight patients
We tested limits for three later stimulation pulses in public SEEG data from eight patients. The source was OpenNeuro ds004696, version 1.0.1. We used 86 sites and 886 site-to-readout pairs. Each fit used calibration errors from the other seven patients. The target required all selected readouts on all three pulses to be covered at 20–500 ms. Site block pooling used one maximum over three donor pulses at each site. Pulse pooling used the three scores separately. The equal-patient mean block coverage increased from 79.4% to 95.1%. The mean normalized radius increased by 48.3%, from 2.44 to 3.61. The fixed upper 90% score increased from 3.98 to 4.15; a smaller score is better. The pulse-minus-block score difference was -0.17, with a descriptive 95% interval of -1.04 to 0.83. The interval kept donor fits fixed. Higher coverage did not give a lower mean primary score. A separate patient-maximum rank rule had only seven donor units. It returned infinity for a 90% request and a finite maximum at 87.5%. The study does not establish exchangeability, an effect specific to neural activity, or online control. The package preserves exact inputs, source hashes, code, results, four figures, and reproduction commands. Fresh source downloads for two patients reproduced all eight main result tables exactly.
SEEG · electrical stimulation · prediction limits · conformal prediction · coverage · human limbic system · brain-computer interfaces
References
5- usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f
Its source extraction lineage defined the public dataset version, derivative sources, adjacent contact readouts, and source quality restrictions used here. The package preserves that lineage and source hashes.
- usesAn offline two-pulse site rank did not show lower 20–500 ms SEEG forecast error at a fixed budget in eight sessions sci:sha256:578806530d9c396756538b53e11352e83c900274801f852ef7211403fa594c3c
It supplied the exact centered trial Gram matrices inherited through the cited input archive. Those matrices let us calculate waveform RMS errors for all selected readouts and fixed windows without the large voltage files.
- usesThree-pulse RMS bounds gave mean coverage of 72.2 percent for later SEEG pulses and 38.1 percent for five-pulse sets at 20–500 ms in eight sessions sci:sha256:8e1cf558fd390a788187427bad722e0296b418b595298fe525f54511fe417f43
We used its 24 exact numerical input files, source retrieval code, audit code, and corrected chronological pulse maps. We changed the target to the final three good pulses and tested transfer from other patients.
- usesdoi:10.18112/openneuro.ds004696.v1.0.1
The analysis used OpenNeuro ds004696 version 1.0.1 recordings and derivatives.
- doi:10.1523/JNEUROSCI.2201-22.2023
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesVariation in four early pulses gave lower SEEG error-limit scores than response energy at 20–500 ms in five patients
Its donor-patient joint block rank test supplied the comparison framework. We fixed joint block pooling and tested a new local variation scale in a different public SEEG cohort.
- usesSEEG bands with fitted shapes had 6.8% lower normalized half-width than constant bands on average for 20–500 ms responses at 86 sites in eight patients
Its pooled calibration study motivated donor patient limits and careful unit counts. This study refitted donor limits during patient resampling. The endpoint and pulse split differ.