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Smaller scaled contact numbers ranked seizure onset labels with mean AUC 0.676 in two short SEEG records for each of 36 patients

We tested whether a fixed low frequency power score adds seizure onset ranking value beyond scaled contact number. We used two 120-second public SEEG records for each of 36 patients. Smaller scaled contact numbers gave mean patient AUC 0.676. A position model gave the same ranking. Adding power raised mean AUC to 0.705. The gain was 0.0285, with a primary patient bootstrap interval of -0.0043 to 0.0629. This interval is conditional on fitted test predictions. Whole patients were held out from model training. An added bootstrap with model refitting also gave an interval that includes zero. At adjacent opposite-label contacts, the power score gave a mean pair ordering rate of 0.508. At equal scaled positions across shafts, its rate was 0.611 in an added exploratory check. The package contains code, 72 checked feature files, source versions, model fits, predictions, figures, and source retrieval instructions. Contact number does not measure anatomy. This single-centre study reuses an earlier cohort and does not show clinical benefit.

stereoelectroencephalography · seizure onset zone · contact ranking · low frequency power · scaled contact number · epilepsy

Admitted 6 citing publications

References

3
  1. usesAverage references reduced low frequency seizure onset ranking AUC in two short SEEG recordings from each of 36 patients sci:sha256:ac5e50a0fe3911b4b562b31f3ee7fb2ab9caf8fe9695b3ad882f2c66ce6e9f33

    We used all 72 checked SEEG feature files, the source metadata, and the pinned source retrieval manifests. We added a scaled contact number baseline, models tested on held-out patients, restricted pair lists, and independent numerical checks. This study uses the same cohort and is not an independent clinical validation.

  2. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analysis used the two 120-second interictal records per patient from OpenNeuro ds004100 version 1.1.3.

  3. doi:10.1093/brain%2Fawab480

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