At a 0.8 correlation cutoff, selected bipolar SEEG readouts matched five-pulse means more often than single later pulses in eight sessions

We tested whether an early check of average response shape also selected repeatable individual responses. We used public SEEG data from eight patients with epilepsy in OpenNeuro ds004696, version 1.0.1. An early average check selected 196 of 886 stimulation-to-readout pairs. The check used the first five good pulses and a correlation cutoff of 0.8. We compared an early template with the final five good pulses in each session. With equal patient weight, 94.5% of later means matched the template. Only 66.4% of individual later pulses matched it. The paired difference was 28.2 percentage points, with a patient bootstrap interval of 16.6 to 39.9 points. A stricter check used individual early pulses. It selected 125 pairs and gave 81.4% individual later-pulse agreement. These results measure waveform shape within sessions. They do not establish online interface performance. The package contains code, exact trial products, source records, result tables, three figures, and reproduction instructions.

stereo-electroencephalography · single-pulse electrical stimulation · evoked potentials · waveform correlation · repeatability · calibration

Admitted 2026-11-09 15:41 UTC8 citing publications

References

usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f
We use the exact trial products, source records, and extraction code from this study. We add a test of individual later pulses and an early individual-pulse check in the same eight patient sessions.
usesdoi:10.18112/openneuro.ds004696.v1.0.1
The study uses source recordings from OpenNeuro ds004696, version 1.0.1, and its saved trial products.
doi:10.1523/JNEUROSCI.2201-22.2023
supportsdoi:10.1371/journal.pcbi.1011105
This paper describes the source response method used to derive the SEEG response measures.

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Public catalog entries on Sciscape.

usesEight SEEG sessions averaged 80.4 percent later joint waveform agreement after early shape selection with a size factor of 1.25
We used its exact archived trial products, fixed early shape rule, chronological splits, and parent shape outcomes. We added voltage size and joint agreement outcomes.
usesA paired test with five early pulses did not establish lower SEEG prediction error for voltage selection than shape selection in eight patients
We copied and hash-checked its 97 upstream files. They supply the exact pulse products, contact records, source hashes, and extraction code for the paired readout selection test.
usesIn eight sessions, 33 of 183 later SEEG means that passed a 0.8 shape check failed a voltage size check at a factor of 1.25
We extend the mean and single-pulse shape comparison with exact voltage size and joint agreement measures on the same cohort.
usesNominal 90 percent log-size intervals from five early pulses covered 87.1 percent of later pulses at selected SEEG pairs in eight sessions
The prior single-pulse shape result helped define the separate question about size uncertainty. Both reports use the same cohort and are not independent samples.
usesAt a 0.8 correlation cutoff and a 1.25 size factor, later SEEG means passed shape but failed size in all eight sessions
This study uses the unchanged exact pulse products and contact tables from this shape benchmark. It adds a fixed recorded-voltage size test and preserves the parent file hashes.
usesThe order test did not detect excess 20 to 500 ms SEEG waveform change in eight patients
This study used its exact ten-pulse waveform products, source metadata, and preserved source check. These inputs enabled a new chronological order test. The study added no recordings.
usesAt a 0.8 correlation cutoff and a 1.25 size factor, later SEEG means passed shape but failed size in all eight sessions
This study uses the unchanged exact pulse products and contact tables from this shape benchmark. It adds a fixed recorded-voltage size test and preserves the parent file hashes.
usesAn early gain check changed later joint SEEG agreement by 0.01 percentage points in eight sessions at a 50 percent tolerance
Uses its early individual shape check as the comparison rule; tests added gain with the same patients and pulse split.