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Under a fixed mean test, load contrasts differed by phase in later sessions of 12 SEEG patients and two fMRI samples

We tested whether high-minus-low load response vectors share structure and differ between encoding and delay. Separate human studies supplied SEEG and fMRI. Cross-block products used scale estimates from an unused third block. First tests used 11 SEEG patients and 16 and 11 fMRI adults. All shared claims failed. Phase-change means were 0.03422, 1.15524 and 0.36559. A separate fixed follow-up processed all 42 unused electrical sessions in the 12 reserved patients. 39 sessions in 12 eligible patients entered its primary; sessions were averaged within people. The new electrical phase-change mean was 0.12172, with 95% person t interval [0.03002, 0.21342]. The later-session phase-change test passed the fixed numerical rule in all three study groups. Its four-claim Holm p was 0.0277974. Shared-structure tests failed. Correct-only and history checks were uncertain. The follow-up reuses people and known MRI scores; it is not independent cross-modal confirmation. A common-code simulation gave positive ordinary squared distance without true change. A gain change alone gave positive corrected change. The nominal shared-structure t test also had an 8% false-positive rate at a 5% level in one specified noise model. Source selection, adaptive trial history, measurement filters and distinct cohorts limit inference. The package adds 3.40 MB of compact phase data from 6.11 GB of checked raw inputs, code, plans, all scores, figures, audits and repeat steps. It does not establish a common neural code or causality.

working memory · SEEG · fMRI · cross-validation · load contrast · phase change · public data · replication

Admitted 7 citing publications

References

11
  1. usesFixed tests did not confirm shared load or phase changes in response spread in 12 SEEG patients and two fMRI samples sci:sha256:d1e3679b2da22e5c32e420354d1e433cc7301d780f5e8f6b53b9e2c359fa757a

    Unchanged equal-window session 01 electrical features, source audits and MRI extraction code.

  2. In one session of 15 patients, SEEG load decoders showed no clear cross-period transfer, while pooled training showed no significant loss sci:sha256:107a7d1ff4f20e7663f455558771404dbda131d8f3c973878a2c1f5057cf597e

    Earlier cross-period classifiers in the source electrical cohort motivate a direct change test; not a new-cohort replication.

  3. usesA second fitted load pattern raised mean test error in 12 SEEG patients and 16 fMRI adults sci:sha256:957819a5e22f1f7f704edf4006247457f5c7fe5bcc06b9099d1bf430d2a9ddf2

    Original author-table MRI parser, reused through SCI 718584a2.

  4. doi:10.7554/eLife.78677
  5. doi:10.18112/openneuro.ds004752.v1.0.1
  6. doi:10.1038/s41467-019-08840-8
  7. doi:10.18112/openneuro.ds001634.v1.0.1
  8. doi:10.18112/openneuro.ds001635.v1.0.1
  9. doi:10.1016/j.neuroimage.2015.12.012
  10. doi:10.1371/journal.pcbi.1005508
  11. doi:10.1016/j.neuroimage.2023.120258

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