The mean ratio of consecutive to arbitrary squared SEEG waveform distances was 0.992 at 20–500 ms in eight patients
We tested waveform changes between consecutive retained stimulation pulses in public OpenNeuro ds004696 version 1.0.1. The sample had eight patients with epilepsy, 86 sites, and 886 bipolar readouts. It contained 1,042 retained pulse records. The equal-patient mean ratio of consecutive to arbitrary squared waveform distances was 0.992 at 20–500 ms. Its descriptive 95 percent patient bootstrap interval was 0.968–1.013. The descriptive patient interval included one. A uniform random order has an exact conditional mean ratio of one. The fixed 20–100 ms check gave a ratio of 0.971, with an interval of 0.945–0.991. This was a secondary result. A source audit found one pair of duplicate waveform records. Removal of one record changed the primary mean by 0.000164. A ratio near one cannot establish independent pulse noise because a component shared by all pulses cancels. The package contains all-pulse products, three figures, source code, hash checks, results, and a retrieval recipe. This audit does not test online control or a clinical stimulation rule.
SEEG · electrical stimulation · pulse order · waveform distance · calibration
References
8- usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f
Used its fixed site and bipolar readout rules, and its mapping of source waveform rows to chronological pulse records.
- usesLater pulse variation accounted for 72.1 percent of normalized 20–500 ms SEEG error for a scaled five-pulse forecast in eight patient sessions sci:sha256:c76a9848dd987107c345f703e31ff3d9949bd3aa3139c35402abe9f6e2470688
Used its source extraction code and verified ten-record pulse products to check every inherited first/final-five product. Its noise assumptions motivated this order audit.
- usesA joint pulse exchangeability test did not detect excess SEEG waveform separation at 20 to 500 ms in eight patient sessions sci:sha256:cedc3626502107ece258475063f448afe88f13e28f33cfeeefc02a1529f3df8f
Used its prior first-to-final pulse comparison to define the new all-record consecutive-distance question.
- usesdoi:10.18112/openneuro.ds004696.v1.0.1
The analysis uses the public SEEG derivatives and source metadata from OpenNeuro ds004696 version 1.0.1.
- doi:10.1523/JNEUROSCI.2201-22.2023
- doi:10.1111/epi.17528
- supportsdoi:10.1214/aoms%2F1177731677
This paper provides the successive-difference ratio cited for the order statistic.
- doi:10.1371/journal.pcbi.1011105
Cited by
10 publicationsPublic catalog entries on Sciscape.
- usesA joint exchangeability test did not detect excess 20–500 ms waveform change across 86 SEEG sites in eight sessions
Used its duplicate-record audit to check the retained first-five and final-five pulse groups. Both reported duplicate source rows at sub-08 RC1-RC2 are excluded from these groups. The original audit and the new exclusion check are preserved.
- usesTwo components from five early pulses captured 29.8 percent of later SEEG variation at 20 to 500 ms after removal of the early mean direction in eight patients
Uses its exact all-pulse Gram matrices, selection tables, source metadata, pinned source receipts, extraction recipe, and known duplicate-record provenance. The new analysis tests transfer of residual waveform components from the first five pulses to later pulses. This is the same cohort, not an independent replication.
- usesA fixed spatial noise rule gave no clear 20 to 500 ms AUC gain after five early pulses in eight SEEG sessions
The duplicate middle-record finding was used to audit the first-five and final-five pulse split.
- usesThree spread pulse records had higher mean normalized 20–100 ms SEEG forecast error than nearby records at equal mean times in eight patients
Uses the complete all-pulse Gram products, chronological row maps, pinned source receipts, and source extraction code. Its early order result motivated this separate, time-matched forecast test. All imported products were hash-checked; a fresh patient 05 extraction matched all arrays.
- usesThree spread pulse records had higher mean normalized 20–100 ms SEEG forecast error than nearby records at equal mean times in eight patients
Uses the complete all-pulse Gram products, chronological row maps, pinned source receipts, and source extraction code. Its early order result motivated this separate, time-matched forecast test. All imported products were hash-checked; a fresh patient 05 extraction matched all arrays.
- usesA geometric median reduced 20–500 ms SEEG error with one simulated gain error among five calibration pulses in eight patients
The imported complete pulse Gram products trace to this archive. The new study uses those inner products to fit median templates and score unchanged later pulses.
- usesThe measured mean rate of consecutive large SEEG forecast errors increased by 0.82 percentage points after pulses in eight people
This study uses its question about pulse order as prior context. That study measured mean distances between consecutive waveforms. This study measures consecutive large forecast error flags. The cohorts and scores differ. This is not an independent replication from new people.
- usesFour frequency scales did not show lower mean 20–500 ms centered bipolar SEEG forecast error than one scale at 86 selected sites in eight sessions with five calibration pulses
Its source audit reported duplicate waveform records. We cite that issue and check the selected duplicate records in the fixed sample.
- usesClock time weights increased mean SEEG forecast error at 20–500 ms with matched decay rates in eight sessions
Use its all-pulse SEEG Gram products, event times, site and readout rules, source hashes, and extraction code. Fresh source checks for patients 01 and 02 matched its products exactly.
- usesThe mean response minus pre-pulse SEEG order score was 0.001 at 15 fixed readouts in five sessions at 20 to 500 ms
This prior audit compared consecutive and arbitrary waveform distances and explained the exact uniform-order reference and its independence limit. The new endpoint compares far and neighboring distances and subtracts a reflected pre-pulse score. Prior early-window results informed the fixed window checks.