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The mean ratio of consecutive to arbitrary squared SEEG waveform distances was 0.992 at 20–500 ms in eight patients

We tested waveform changes between consecutive retained stimulation pulses in public OpenNeuro ds004696 version 1.0.1. The sample had eight patients with epilepsy, 86 sites, and 886 bipolar readouts. It contained 1,042 retained pulse records. The equal-patient mean ratio of consecutive to arbitrary squared waveform distances was 0.992 at 20–500 ms. Its descriptive 95 percent patient bootstrap interval was 0.968–1.013. The descriptive patient interval included one. A uniform random order has an exact conditional mean ratio of one. The fixed 20–100 ms check gave a ratio of 0.971, with an interval of 0.945–0.991. This was a secondary result. A source audit found one pair of duplicate waveform records. Removal of one record changed the primary mean by 0.000164. A ratio near one cannot establish independent pulse noise because a component shared by all pulses cancels. The package contains all-pulse products, three figures, source code, hash checks, results, and a retrieval recipe. This audit does not test online control or a clinical stimulation rule.

SEEG · electrical stimulation · pulse order · waveform distance · calibration

Admitted 10 citing publications

References

8
  1. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    Used its fixed site and bipolar readout rules, and its mapping of source waveform rows to chronological pulse records.

  2. usesLater pulse variation accounted for 72.1 percent of normalized 20–500 ms SEEG error for a scaled five-pulse forecast in eight patient sessions sci:sha256:c76a9848dd987107c345f703e31ff3d9949bd3aa3139c35402abe9f6e2470688

    Used its source extraction code and verified ten-record pulse products to check every inherited first/final-five product. Its noise assumptions motivated this order audit.

  3. usesA joint pulse exchangeability test did not detect excess SEEG waveform separation at 20 to 500 ms in eight patient sessions sci:sha256:cedc3626502107ece258475063f448afe88f13e28f33cfeeefc02a1529f3df8f

    Used its prior first-to-final pulse comparison to define the new all-record consecutive-distance question.

  4. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis uses the public SEEG derivatives and source metadata from OpenNeuro ds004696 version 1.0.1.

  5. doi:10.1523/JNEUROSCI.2201-22.2023
  6. doi:10.1111/epi.17528
  7. supportsdoi:10.1214/aoms%2F1177731677

    This paper provides the successive-difference ratio cited for the order statistic.

  8. doi:10.1371/journal.pcbi.1011105

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