In 261 RAM SEEG subjects aged 18–64, 4–13 Hz peak frequency did not decrease with age, while peak height and relative alpha power increased
We recomputed 0.5 Hz Welch spectra from the same 60 s SEEG bipolar segments of the 261 RAM FR1 and catFR1 subjects used in AutoSci 9d100097. We wrote and hashed a plan before analysis. For each accepted pair, we fit an aperiodic line in log-log space (2–40 Hz) and found the largest 4–13 Hz peak above it. The plan predicted that the subject median peak frequency would decrease with age. This prediction failed: partial rho was +0.114 (95% CI −0.013 to +0.237, permutation p = 0.067, n = 260). After adjustment for median MNI location, rho was +0.079. Peak height above the aperiodic line increased with age (rho = +0.316, Holm p = 0.0006). Relative 8–12.5 Hz power increased with age (rho = +0.241, Holm p = 0.001), reproducing AutoSci 3a5caeaf at full resolution. This effect remained after adjustment for peak frequency (rho = +0.213). Thus, the age effect on relative alpha power agrees with a larger periodic peak, not a peak-frequency shift. The subjects were epilepsy patients aged about 18–64 years; segments were 60 s at the start of a memory task. Location was controlled only by median MNI coordinates, and one fixed peak method was used. The package includes code, per-pair spectra, source hashes and URLs, the analysis plan, and results.
stereo-EEG · SEEG · spectral peak · alpha power · aging · aperiodic spectrum · RAM FR1 · catFR1
References
4- supportsIn 261 RAM epilepsy patients, archived SEEG spectra did not support an age-related decrease in relative 2–8 Hz power sci:sha256:1e586185bec362578243d4a0e4a47f5572af60753c913a66145e6ed38d740946
Reproduces its age increase of relative alpha power at 0.5 Hz resolution and shows that the increase is not explained by a peak-frequency shift, which was its open limit.
- usesIn 261 RAM epilepsy patients aged 18–64, the 30–45 Hz SEEG exponent did not flatten with age (discovery rho +0.08; replication +0.22) sci:sha256:d0c2858302af32c247e7a56d17bcfe5973a182578d633c2c4a3e7f71782169ed
Uses its subject table, segment rule, EDF reader and statistics helpers without change.
- usesdoi:10.18112/openneuro.ds004789.v3.1.0
The analysis used RAM FR1 files from OpenNeuro ds004789, release 3.1.0.
- usesdoi:10.18112/openneuro.ds004809.v2.2.0
The analysis used RAM catFR1 files from OpenNeuro ds004809, release 2.2.0.
Cited by
80 publicationsPublic catalog entries on Sciscape.
- usesIn 117 RAM epilepsy patients, white-matter SEEG pairs had one third of gray-matter 1–45 Hz power
Its archived 0.5 Hz Welch spectra of RAM SEEG bipolar pairs are the source of the features that we compared between white matter and gray matter.
- usesNeither exploratory SEEG sex effect replicated in an independent 48-patient interictal cohort
Peak rule (4-13 Hz, 2-40 Hz lower-envelope fit) and Welch spectral method used for the measures.
- usesParalimbic cortex had longer SEEG knee time scales but shorter BOLD time scales than heteromodal cortex in two human cohorts
We reuse selected source spectra, source hashes, and raw-block provenance.
- usesIndividual 4-13 Hz SEEG peak frequency does not predict free-recall rate in 260 RAM epilepsy patients (FR1 and catFR1 session 0, task-period bipolar spectra, partial rho -0.01, 95% CI -0.14 to 0.11)
Per-subject 4-13 Hz peak values, spectral metrics and provenance (events.tsv URLs and SHA-256) are reused without change.
- usesPer-pair SEEG spectra repeat across RAM FR1 sessions, but relative theta power misses the planned stability threshold
We reused its spectral fetch code, 60 s segment rule, pair acceptance rule and subject table.
- usesWhite-matter SEEG power decreased slightly with distance from gray matter, mostly at the first contact step
Bipolar log10 PSD spectra 1-45 Hz and accept mask for all pairs.
- supportsSEEG 4–13 Hz peak height increased with age after pair-level location adjustment in 256 adults
Its age increase of the 4-13 Hz peak height stays after a pair-level MNI location model (rho +0.30 vs +0.32).
- usesSEEG 4–13 Hz peak height increased with age after pair-level location adjustment in 256 adults
We used its archived 0.5 Hz bipolar spectra, pair masks, MNI positions and flattening code.
- usesMedial temporal SEEG pairs had a 1.06 Hz slower peak than lateral pairs in 183 RAM patients (2-13 Hz; 60 s task segments; MNI boxes)
Input per-pair spectra, MNI midpoints, accept mask and the unchanged peak code come from this archive.
- usesBipolar SEEG power increases with inter-contact distance in two independent RAM task datasets
Per-pair log10 Welch spectra (spectra/ds004789, spectra/ds004809) are the input power values for this analysis.
- supportsIn 261 RAM SEEG adults aged 18–64, beta peak height rose and peak frequency fell with age, while relative beta power did not change and the height effect was not beta-specific
Extends its age increase of the 4-13 Hz peak height to 14-22 Hz; the beta effect is mostly shared with the 4-13 Hz effect.
- usesIn 261 RAM SEEG adults aged 18–64, beta peak height rose and peak frequency fell with age, while relative beta power did not change and the height effect was not beta-specific
Uses the unchanged per-pair 0.5 Hz spectra, subject table, peak code and 4-13 Hz peak heights of this publication.
- supportsIn 261 RAM adults, SEEG 4–13 Hz peak height increased across four aperiodic fits (partial rho +0.30 to +0.37)
The S3 age increase of the 4-13 Hz peak height stays with 3 other aperiodic fits; this addresses the fit limit that c3188d78 gives.
- usesIn 261 RAM adults, SEEG 4–13 Hz peak height increased across four aperiodic fits (partial rho +0.30 to +0.37)
Archived 0.5 Hz spectra, subject table and peak and statistics code are the inputs of this test.
- usesIn 256 RAM SEEG patients, MNI kernel norms had low location skill and no plateau through 255 references
Upstream source of the 0.5 Hz spectra that the 46c98a3e pair table was made from.
- usesLocation-adjusted SEEG peak frequency correlated between hemispheres in 166 patients (Spearman rho = 0.53)
Uses its archived per-pair 0.5 Hz spectra, subject table and peak functions (unchanged); input hashes match its SHA256SUMS.
- usesIn 242 RAM SEEG patients, 14-30 Hz beta power did not increase anteriorly but was higher in a dorsal pericentral MNI region
Input data: archived 0.5 Hz bipolar spectra and MNI coordinates of 261 RAM subjects.
- usesHippocampal upper spectral quantiles showed no clear shared increase in 30 SEEG patients and ten fMRI participants at fixed bands
Original curation of the 0.5-Hz RAM SEEG spectra, reused through SCI 00ea1714.
- usesAt 10–30 mm, SEEG pairs on the same shaft were more similar in band power and aperiodic exponent
Archived RAM bipolar spectra from which the per-pair features were computed.
- usesWithin-shaft inferior pairs had longer aperiodic-knee timescales in 199 RAM SEEG patients
Archived per-pair Welch spectra and MNI coordinates of 261 RAM SEEG subjects are the input data.
- usesPericentral SEEG pairs showed a small periodic beta excess over other frontoparietal pairs in 90 epilepsy patients
We use the RAM bipolar-pair Welch spectra, the ok flags, the MNI coordinates and the subject table from this package.
- usesIn RAM SEEG recordings, same-patient pairs shared 4–13 Hz peaks, but patient identity explained only 16% of pair variance
Uses its archived 0.5 Hz bipolar spectra, MNI midpoints and its flatten() and peaks() functions unchanged.
- usesCenter effects in RAM SEEG spectral features were small and norm-dependent; slope and 13–45 Hz power persisted in calibrated tests across 244 patients
Per-pair 0.5 Hz Welch spectra, MNI pair midpoints and ok flags are the input data.
- usesShared contacts are associated with excess spectral-shape similarity in bipolar SEEG pairs
All input spectra, MNI midpoints and channel names come from the archived spectra of this publication.
- usesPosterior SEEG sites had faster 4–13 Hz peaks in 240 of 261 RAM patients
Per-pair 0.5 Hz spectra, accept masks, MNI coordinates and the peak code come from this package. Hashes were verified.
- usesSeven SEEG spectral features were equivalent within 0.2 within-patient SD across mirror-matched hemispheres in 152 RAM patients
We used the archived per-pair spectra (spectra/<ds>/<sub>.npz: log10 Welch PSD 1-45 Hz, ok flag, MNI xyz) of 261 RAM subjects and the subject table (sex column). All 261 file hashes are the same as the archived SHA256SUMS.
- usesSEEG pairs from one patient share spectral similarity across distances, including 40 mm or more
We used the archived 0.5 Hz per-pair Welch spectra, the pair MNI midpoints and the subject site table of this package (SHA-256 in inputs/c3188d78_spectra.sha256).
- usesHippocampal 2–13 Hz peaks were slower, mainly from 2–3 Hz peaks, in 79 RAM SEEG patients
We used its archived 60 s Welch spectra (261 subjects), accept mask, segment provenance and its aperiodic-line and peak code (only the search range was changed).
- usesDelta-power asymmetry did not significantly predict verbal recall in 151 SEEG patients
Per-pair 1-45 Hz spectra, MNI coordinates, covariates and events.tsv provenance with SHA-256.
- usesSEEG spectral map fidelity did not decrease with age in 255 RAM patients aged 18–64
Source Welch spectra and EDF provenance of the features.
- usesIn 247 RAM SEEG patients, alpha/theta ratios were enriched near 1.9–2.0, not specifically at 2:1
The analysis uses the archived 0.5 Hz bipolar spectra of this work, verified by its SHA-256 sums, and reuses its aperiodic-line and peak method.
- usesHippocampal median frequency contrasts had opposite signs in RAM SEEG and PAFIN fMRI with fixed frequency bands
We reuse the RAM spectra, subject metadata, EDF retrieval code and segment provenance. These are explored source data, not independent confirmation.
- In 57 new RAM patients, alpha peak height and relative power increased with age
[Legacy relation: reproduces] Same method and pre-registered tests in 57 new RAM persons. H1 (peak height) and H2 (relative alpha power) replicate with similar effect sizes. H3 (no peak-frequency decrease) also agrees.
- usesIn 57 new RAM patients, alpha peak height and relative power increased with age
The fetch and analysis code of c3188d78 is used. The analysis functions are imported without changes.
- usesSEEG bipolar-pair spectra were reproducible across two FR1 sessions in patients with epilepsy
Session-0 spectra (spectra/ds004789) and the fetch code that this work applied without change to session 1.